Compile Data Set for Download or QSAR
Found 205 of ki data for polymerid = 50000974
TargetTryptase beta-2(Homo sapiens (Human))
Axys Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50093142(1,5-di{4-[4-amino(imino)methylaminobenzylcarbamoyl...)copy SMILEScopy InChI
Affinity DataKi:  0.0700nMAssay Description:Inhibitory activity against human tryptase enzymeMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q21835S6PubMed
TargetTryptase beta-2(Homo sapiens (Human))
Axys Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50101018(1,4-di{4-[4-amino(imino)methylphenylcarboxamidomet...)copy SMILEScopy InChI
Affinity DataKi:  0.400nMAssay Description:Inhibitory activity against human tryptase enzymeMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q21835S6PubMed
TargetTryptase beta-2(Homo sapiens (Human))
Axys Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50084616(CHEMBL310290 | [(4-Aminomethyl-benzylcarbamoyl)-me...)copy SMILEScopy InChI
Affinity DataKi:  0.600nMAssay Description:Inhibitory potency against tryptaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NP23NXPubMed
TargetTryptase beta-2(Homo sapiens (Human))
Axys Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50156461(3-[4-(5-Aminomethyl-2-fluoro-phenyl)-piperidine-1-...)copy SMILEScopy InChI
Affinity DataKi:  1.30nMAssay Description:Inhibitory activity against human mast cell tryptase betaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KH0MSTPubMed
TargetTryptase beta-2(Homo sapiens (Human))
Axys Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50156460(3-[4-(3-Aminomethyl-phenyl)-piperidine-1-carbonyl]...)copy SMILEScopy InChI
Affinity DataKi:  1.5nMAssay Description:Inhibitory activity against human mast cell tryptase betaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KH0MSTPubMed
TargetTryptase beta-2(Homo sapiens (Human))
Axys Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50093132(CHEMBL75749 | [3-(4-Guanidino-benzyl)-ureido]-acet...)copy SMILEScopy InChI
Affinity DataKi:  2nMAssay Description:Inhibitory potency against tryptaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NP23NXPubMed
TargetTryptase beta-2(Homo sapiens (Human))
Axys Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50411015(CHEMBL539086)copy SMILEScopy InChI
Affinity DataKi:  2.30nMAssay Description:Inhibition of human B tryptaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G44RHPPubMed
TargetTryptase beta-2(Homo sapiens (Human))
Axys Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50411006(CHEMBL539088)copy SMILEScopy InChI
Affinity DataKi:  2.5nMAssay Description:Inhibition of human B tryptaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G44RHPPubMed
TargetTryptase beta-2(Homo sapiens (Human))
Axys Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50411011(CHEMBL537868)copy SMILEScopy InChI
Affinity DataKi:  2.90nMAssay Description:Inhibition of human B tryptaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G44RHPPubMed
TargetTryptase beta-2(Homo sapiens (Human))
Axys Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50093143(CHEMBL76733 | N-(4-Aminomethyl-benzyl)-N'-(4-{[3-(...)copy SMILEScopy InChI
Affinity DataKi:  3nMAssay Description:Inhibitory potency against tryptaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NP23NXPubMed
TargetTryptase beta-2(Homo sapiens (Human))
Axys Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM14312(CHEMBL214368 | CRA23 | ethyl N-[(2S)-6-amino-1-(5-...)copy SMILEScopy InChI
Affinity DataKi:  3nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
TargetTryptase beta-2(Homo sapiens (Human))
Axys Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50411017(CHEMBL539603)copy SMILEScopy InChI
Affinity DataKi:  3.25nMAssay Description:Inhibition of human B tryptaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G44RHPPubMed
TargetTryptase beta-2(Homo sapiens (Human))
Axys Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50411009(CHEMBL538574)copy SMILEScopy InChI
Affinity DataKi:  3.70nMAssay Description:Inhibition of human B tryptaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G44RHPPubMed
TargetTryptase beta-2(Homo sapiens (Human))
Axys Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50411002(CHEMBL556994)copy SMILEScopy InChI
Affinity DataKi:  3.75nMAssay Description:Inhibition of human B tryptaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G44RHPPubMed
TargetTryptase beta-2(Homo sapiens (Human))
Axys Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM14311(CRA22 | N-[(2S)-6-amino-1-(5-{[4-(2,3-dihydro-1H-i...)copy SMILEScopy InChI
Affinity DataKi:  4nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W09450PubMed
TargetTryptase beta-2(Homo sapiens (Human))
Axys Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50156457(CHEMBL186730 | [4-(5-Aminomethyl-2-fluoro-phenyl)-...)copy SMILEScopy InChI
Affinity DataKi:  4.30nMAssay Description:Inhibitory activity against human mast cell tryptase betaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KH0MSTPubMed
TargetTryptase beta-2(Homo sapiens (Human))
Axys Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50411013(CHEMBL534493)copy SMILEScopy InChI
Affinity DataKi:  4.60nMAssay Description:Inhibition of human B tryptaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G44RHPPubMed
TargetTryptase beta-2(Homo sapiens (Human))
Axys Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50410996(CHEMBL537647)copy SMILEScopy InChI
Affinity DataKi:  4.70nMAssay Description:Inhibition of human B tryptaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G44RHPPubMed
TargetTryptase beta-2(Homo sapiens (Human))
Axys Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50093131(CHEMBL80210 | [(4-Aminomethyl-benzylcarbamoyl)-met...)copy SMILEScopy InChI
Affinity DataKi:  5nMAssay Description:Inhibitory potency against tryptaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NP23NXPubMed
TargetTryptase beta-2(Homo sapiens (Human))
Axys Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50093133(CHEMBL79822 | N-(4-Aminomethyl-benzyl)-N'-[4-({[3-...)copy SMILEScopy InChI
Affinity DataKi:  5nMAssay Description:Inhibitory potency against tryptaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NP23NXPubMed
TargetTryptase beta-2(Homo sapiens (Human))
Axys Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM16127(2,2 -methanediylbis(1H-benzimidazole-6-carboximida...)copy SMILEScopy InChI
Affinity DataKi:  5nM ΔG°:  -11.2kcal/molepH: 8.2 T: 2°CAssay Description:Enzymes were incubated with inhibitors at eight inhibitor concentrations bracketing the Ki, prepared by serial dilution along with control lacking th...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29P2ZW9PubMed
TargetTryptase beta-2(Homo sapiens (Human))
Axys Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50411019(CHEMBL558199)copy SMILEScopy InChI
Affinity DataKi:  5nMAssay Description:Inhibition of human B tryptaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G44RHPPubMed
TargetTryptase beta-2(Homo sapiens (Human))
Axys Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50411005(CHEMBL537646)copy SMILEScopy InChI
Affinity DataKi:  5nMAssay Description:Inhibition of human B tryptaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G44RHPPubMed
TargetTryptase beta-2(Homo sapiens (Human))
Axys Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50187800((S)-ethyl 1-(5-(4-phenethoxybenzyl)-1,2,4-oxadiazo...)copy SMILEScopy InChI
Affinity DataKi:  5.40nMAssay Description:Binding affinity to human tryptase beta2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X929W7PubMed
TargetTryptase beta-2(Homo sapiens (Human))
Axys Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50187800((S)-ethyl 1-(5-(4-phenethoxybenzyl)-1,2,4-oxadiazo...)copy SMILEScopy InChI
Affinity DataKi:  5.40nMAssay Description:Inhibition of human B tryptaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G44RHPPubMed
TargetTryptase beta-2(Homo sapiens (Human))
Axys Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50411001(CHEMBL558763)copy SMILEScopy InChI
Affinity DataKi:  5.70nMAssay Description:Inhibition of human B tryptaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G44RHPPubMed
TargetTryptase beta-2(Homo sapiens (Human))
Axys Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50411008(CHEMBL535836)copy SMILEScopy InChI
Affinity DataKi:  5.80nMAssay Description:Inhibition of human B tryptaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G44RHPPubMed
TargetTryptase beta-2(Homo sapiens (Human))
Axys Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM14316((2R)-N-[(2S)-1-(5-{[4-(2,3-dihydro-1H-inden-2-ylca...)copy SMILEScopy InChI
Affinity DataKi:  6nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W09450PubMed
TargetTryptase beta-2(Homo sapiens (Human))
Axys Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50411016(CHEMBL559161)copy SMILEScopy InChI
Affinity DataKi:  6.20nMAssay Description:Inhibition of human B tryptaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G44RHPPubMed
TargetTryptase beta-2(Homo sapiens (Human))
Axys Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50411007(CHEMBL534492)copy SMILEScopy InChI
Affinity DataKi:  6.5nMAssay Description:Inhibition of human B tryptaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G44RHPPubMed
TargetTryptase beta-2(Homo sapiens (Human))
Axys Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50131975(1-(2-Methylamino-3-phenyl-propionyl)-pyrrolidine-2...)copy SMILEScopy InChI
Affinity DataKi:  6.5nMAssay Description:In vitro inhibition of human Tryptase beta.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23T9J0VPubMed
TargetTryptase beta-2(Homo sapiens (Human))
Axys Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50411018(CHEMBL559184)copy SMILEScopy InChI
Affinity DataKi:  6.55nMAssay Description:Inhibition of human B tryptaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G44RHPPubMed
TargetTryptase beta-2(Homo sapiens (Human))
Axys Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50411010(CHEMBL535163)copy SMILEScopy InChI
Affinity DataKi:  6.80nMAssay Description:Inhibition of human B tryptaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G44RHPPubMed
TargetTryptase beta-2(Homo sapiens (Human))
Axys Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50410995(CHEMBL536972)copy SMILEScopy InChI
Affinity DataKi:  7.60nMAssay Description:Inhibition of human B tryptaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G44RHPPubMed
TargetTryptase beta-2(Homo sapiens (Human))
Axys Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50093141(CHEMBL306537 | Pentanedioic acid 4-aminomethyl-ben...)copy SMILEScopy InChI
Affinity DataKi:  9nMAssay Description:Inhibitory potency against tryptaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NP23NXPubMed
TargetTryptase beta-2(Homo sapiens (Human))
Axys Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50410998(CHEMBL535617)copy SMILEScopy InChI
Affinity DataKi:  9.20nMAssay Description:Inhibition of human B tryptaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G44RHPPubMed
TargetTryptase beta-2(Homo sapiens (Human))
Axys Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50411004(CHEMBL535386)copy SMILEScopy InChI
Affinity DataKi:  9.60nMAssay Description:Inhibition of human B tryptaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G44RHPPubMed
TargetTryptase beta-2(Homo sapiens (Human))
Axys Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50411000(CHEMBL558178)copy SMILEScopy InChI
Affinity DataKi:  9.80nMAssay Description:Inhibition of human B tryptaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G44RHPPubMed
TargetTryptase beta-2(Homo sapiens (Human))
Axys Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50112064(3-(3-Aminomethyl-phenyl)-2-(3-{2-[(2R,5S)-5-({2-[2...)copy SMILEScopy InChI
Affinity DataKi:  10nMAssay Description:Inhibitory activity against human Tryptase beta was evaluatedMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MP52MWPubMed
TargetTryptase beta-2(Homo sapiens (Human))
Axys Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50093135(CHEMBL77911 | [(4-Guanidino-benzylcarbamoyl)-methy...)copy SMILEScopy InChI
Affinity DataKi:  10nMAssay Description:Inhibitory potency against tryptaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NP23NXPubMed
TargetTryptase beta-2(Homo sapiens (Human))
Axys Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50410999(CHEMBL557979)copy SMILEScopy InChI
Affinity DataKi:  11nMAssay Description:Inhibition of human B tryptaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G44RHPPubMed
TargetTryptase beta-2(Homo sapiens (Human))
Axys Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50410997(CHEMBL557987)copy SMILEScopy InChI
Affinity DataKi:  17nMAssay Description:Inhibition of human B tryptaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G44RHPPubMed
TargetTryptase beta-2(Homo sapiens (Human))
Axys Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50112065(3-(3-Aminomethyl-phenyl)-2-[2-(2-{(2S,5R)-5-[({[2-...)copy SMILEScopy InChI
Affinity DataKi:  18nMAssay Description:Inhibitory activity against human Tryptase beta was evaluatedMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MP52MWPubMed
TargetTryptase beta-2(Homo sapiens (Human))
Axys Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50410994(CHEMBL536290)copy SMILEScopy InChI
Affinity DataKi:  18nMAssay Description:Inhibition of human B tryptaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G44RHPPubMed
TargetTryptase beta-2(Homo sapiens (Human))
Axys Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50131980(1-Acetyl-pyrrolidine-2-carboxylic acid [1-(benzoth...)copy SMILEScopy InChI
Affinity DataKi:  19nMAssay Description:In vitro inhibition of human Tryptase beta.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23T9J0VPubMed
TargetTryptase beta-2(Homo sapiens (Human))
Axys Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50131984(1-Acetyl-azetidine-2-carboxylic acid [1-(benzothia...)copy SMILEScopy InChI
Affinity DataKi:  20nMAssay Description:In vitro inhibition of human Tryptase beta.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23T9J0VPubMed
TargetTryptase beta-2(Homo sapiens (Human))
Axys Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM14317(CRA28 | N-[(2S)-1-(5-{[4-(2,3-dihydro-1H-inden-2-y...)copy SMILEScopy InChI
Affinity DataKi:  21nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W09450PubMed
TargetTryptase beta-2(Homo sapiens (Human))
Axys Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50131977(1-Acetyl-4-hydroxy-pyrrolidine-2-carboxylic acid [...)copy SMILEScopy InChI
Affinity DataKi:  22nMAssay Description:In vitro inhibition of human Tryptase beta.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23T9J0VPubMed
TargetTryptase beta-2(Homo sapiens (Human))
Axys Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50411003(CHEMBL536973)copy SMILEScopy InChI
Affinity DataKi:  22nMAssay Description:Inhibition of human B tryptaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G44RHPPubMed
TargetTryptase beta-2(Homo sapiens (Human))
Axys Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM14307((2R)-N-[(1S)-1-{[6-amino-1-(1,3-benzothiazol-2-yl)...)copy SMILEScopy InChI
Affinity DataKi:  23nM ΔG°:  -10.3kcal/molepH: 7.4 T: 2°CAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W09450PubMed
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